Endocrine Abstracts

Introduction: Biotin is a water-soluble vitamin involved in several and important metabolic processes, recommended daily intake for adults is 30–100 μg/day and normal plasma concentrations are 0.4–1.2 ng/day. Nowadays biotin is being used in inherited metabolic diseases, multiple sclerosis and as a supplement in, over the counter multivitamins widely used for common hair and skin problems. The supraphysiologic biotin intake has produced emerging problems with bi...